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Elisabetta Verderio Edwards

Elisabetta Verderio Edwards

Professor

School of Science & Technology

Staff Group(s)
Bioscience

Role

Dr Verderio Edwards is:

  • Professor of Biochemistry
  • Academic Coordinator for Research Excellence Framework 2029 (Allied Health Professions, Dentistry, Nursing and Pharmacy)
  • Member of SHiMR steering committee
  • Director of study for PhD projects, MRes/MSc projects and Erasmus/international placements
  • Mentor of post-doctoral fellows (Marie SkÅ‚odowska-Curie Actions MSCA projects on request).

Visit  the Lab website.

Research areas

The extracellular environment and the cross-talk between the ECM (extracellular matrix) and extracellular vesicles as matrix and cell messengers.

The extracellular function of Transglutaminase-2 (TG2) in cell-matrix dynamics and the relationship of this with wound healing, tissue fibrosis and aging.

Extracellular vesicles proteomics/transcriptomics to track disease progression and therapeutic applications of mesenchymal/stromal stem cells extracellular vesicles.

Collaborators

Å·ÃÀ¾ÞÈély much research has been conducted with CNRS- Grenoble Institut de Biologie Structurale, Grenoble (Prof H. Lortat-Jacob), University of Bologna, Department of Biological Sciences (Prof D. Serafini-Fracassini and Prof S. Del Duca), CNR Institute of Neuroscience in Milan (Dr C Verderio), University of Messina (Prof Daniela Caccamo), University of Campania, Precision Medicine (Prof M Caraglia), University of Patras, Department of Nephrology and Renal Transplantation (Prof Dimitris S Goumenos).

In the United Kingdom, a long term collaboration has been with the University of Sheffield, School of Medicine and Biomedical Sciences (Prof Tim Jonson and Dr Phil Watson) and with Prof Dave Abraham, Institute of Immunity and Transplantation, at University College London (UCL).

PhD Projects available in the following areas:

  • Extracellular vesicles -cell and -ECM dynamics
  • Mesenchymal Stem Cells extracellular vesicles in neuronal cell survival
  • Extracellular transglutaminase-2 in aging, neurodegeneration and fibrosis
  • Urinary extracellular vesicles proteomics/transcriptomics and markers of CKD progression

The range of skills I have learned in 6 months from the start of my PhD are amazing. (First Year PhD Student)

The level of guidance and feedback I have received throughout my PhD studies was continuous and of high standard. (Final Year PhD student)

For more information email: elisabetta.verderio-edwards@ntu.ac.uk

Opportunities to carry out postgraduate research towards an MPhil / PhD exist in all the areas identified above and further information may be obtained from the /research/research-degrees-at-ntu.

External activity

  • Member of (MRPharmS)
  • Member of (GPhC)
  • Member of
  • Member of
  • UK Alumna
  • Fellow of the Higher Education Academy
  • Fellow of the Higher Education Academy ()
  • Health Research team of experts
  • Associated Professor (fixed time) at the University of Bologna

Sponsors and collaborators

  • UCB Pharmaceuticals
  • Mestag Therapeutics
  • Chiesi Pharmaceutics
  • BBSRC
  • Eranda Rothschild
  • Tony Marmont foundation
  • Kidney Research
  • Wellcome Trust
  • iNET East Midlands
  • British Council-CRUI
  • EPSRC
  • VU Medical School Amsterdam
  • CNR Institute, Milan
  • FEBS
  • Biochemical Society
  • University of Bologna

Publications

. Tonoli, E., Verduci, I., Gabrielli, M., Prada, I., Forcaia, G., Coveney, C., Savoca, M., Boocock, D.J., Sancini, G., Mazzanti, M., Verderio, C., and Verderio, E.A.M. Prog Neurobiol. 2022, 216:10231.

. Furini, G., Schroeder, N., Huang, L., Boocock, D., Scarpellini, A., Coveney, C., Tonoli, E., Ramaswamy, R., Ball, G., Verderio, C., Johnson, T.S., Verderio, E.A.M. Journal of the American Society of Nephrology. 2018, 29:880-905.

. Burhan, I., Furini, G., Lortat-Jacob, H., Atobatele, A.G., Scarpellini, A., Schroeder, N., Atkinson, J., Maamra, M., Nutter, F.H., Watson, P., Vinciguerra, M., Johnson, T.S, Verderio, E. Scientific Reports. 2016, 6:31343.

. Scarpellini A, Huang L, Burhan I, Schroeder N, Funck M, Johnson TS, Verderio EA. Journal of the American Society of Nephrology. 2014, 25:1013-27.

. Lortat-Jacob H, Burhan I, Scarpellini A, Thomas A, Imberty A, Vivès RR, Johnson T, Gutierrez A, Verderio E, Journal of Biological Chemistry, 2012, 287:18005-18017

. Chou CY, Streets AJ, Watson PF, Huang L, Verderio E, Johnson TS, Journal of Biological Chemistry, 2011, 286:27825-27835

. Iorio RA, Di Sandro A, Paris R, Pagliarani G, Tartarini S,  Ricci G,  Serafini-Fracassini D, Verderio E, Del Duca S, Amino Acids, 2011, 42:1007

. Di Sandro A, Del Duca, S, Verderio E, Hargreaves A, Bonner P, Griffin M, Iorio R, Scarpellini A, Serafini-Fracassini D, Biochemical Journal, 2010, 429: 261-271

. Scarpellini A, Germack R, Lortat-Jacob H, Muramatsu T, Billett E, Johnson T, Verderio E, Journal of Biological Chemistry, 2009, 284:18411-1842

. Telci D, Wang Z, Li X, Verderio EA, Humphries MJ, Baccarini M, Basaga H, Griffin M, Journal of Biological Chemistry, 2008, 283:20937-41

See all of Elisabetta Verderio Edwards's

Press expertise

  • Chronic kidney disease
  • Fibrosis
  • Wound healing
  • Aging
  • Transglutaminase type 2 (TG2)
  • Extracellular vesicles